ME.100 (Biophysics and Biophysical Chemistry)

Critical reading and analysis of primary source literature is vital to scientific discourseand discovery. Students will be responsible for analyzing and critiquing papers in diverse topics and systemsranging from replication, transcription, and translation to enzyme mechanism, drug resistance, innate immunity,and signaling. Methods covered will include structural, biochemical, single-molecule, single-cell, and genomicapproaches. Students will deliver analytic presentations on at least two ground-breaking papers relevant to theseareas, and will be expected to actively participate in class discussion of experimental methodology and logic ofother papers assigned in the course.

The course will cover (1) macromolecules, (2) physical chemical principles dictating their biological behavior, and (3) methods to study them. Lectures will focus on practical application of the methods, experimental design, data collection, and elementary aspects of data analysis.

Thesis research

Laboratory Research